Abstract
To evaluate a new method of measuring the intraocular pressure (IOP) in the vitreous cavity. IOPs in the anterior chamber and vitreous cavities of 24 porcine eyes (12 eyes with lenses and 12 eyes without lenses) were measured directly, continuously, and simultaneously. We used a needle as a part of the pressure sensor to measure the anterior chamber IOP and a disk-shaped sensor to measure the vitreous cavity IOP. A significant group-by-condition interaction on the vitreous cavity IOP between the two groups (phakia and aphakia) and four conditions of anterior chamber IOP were observed (F[3,258] = 5.8564, p < 0.001). A positive correlation was observed between the vitreous cavity IOP and anterior chamber IOP in both the phakia group (R = 0.96, p < 0.001) and the aphakia group (R = 0.97, p < 0.001). No significant correlation was observed between the ΔIOPv-a (vitreous cavity IOP − anterior chamber IOP) and anterior chamber IOP in either group (phakia group: R = − 0.18, p = 0.034; aphakia group: R = − 0.029, p = 0.73). The vitreous cavity IOP measured with the new sensor was well-correlated with the anterior chamber IOP in the physiological range tested.
Highlights
To evaluate a new method of measuring the intraocular pressure (IOP) in the vitreous cavity
The present study shows that the new device without a tubular structure, which was considered to prevent clogging, could measure the vitreous IOP in the vitreous body directly and that vitreous IOP was well-correlated with the anterior IOP in the physiological range studied
We believe that the vitreous IOP in our research was considered close to the true vitreous IOP
Summary
To evaluate a new method of measuring the intraocular pressure (IOP) in the vitreous cavity. A positive correlation was observed between the vitreous cavity IOP and anterior chamber IOP in both the phakia group (R = 0.96, p < 0.001) and the aphakia group (R = 0.97, p < 0.001). Other researchers have reported that, under a certain degree of pressure (< 50 mmHg), the IOP does not differ significantly between the anterior chamber and vitreous cavity without vitreous g els. Other researchers have reported that, under a certain degree of pressure (< 50 mmHg), the IOP does not differ significantly between the anterior chamber and vitreous cavity without vitreous g els6 In this case, the lens had little effect on the differences in IOP. A method to measure the pressure applied to a gel via a strain change has been reported
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
