Abstract
The research work represents the thermodynamic studies of well known flavonoid quercetin in presence of non-ionic surfactant Tween 80. The studies were performed in hydro-ethanolic solvent system (30% v/v ethanol) at five different temperatures (20–40 °C with difference of 5 °C) in order to analyze the changes in thermodynamic properties with respect to temperature change. As Tween 80 is non-ionic surfactant, 1% sodium chloride solution was added as an electrolyte to ensure the flow of electrons. The conductance studies for the flavonoid-surfactant system were carried out and the data thus obtained was utilized to calculate various thermodynamic parameters i.e. standard enthalpy change (ΔHom), standard entropy change (ΔSom) and standard Gibbs free energy change (ΔGom) of micellization. Overall, the effects of quercetin on micellization process of Tween 80 at different temperatures and hydro-ethanolic solvent have been reported.
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