Investigation of HIFU beam propagation through acoustic holograms in water

Abstract

We investigated variations in the HIFU beam of a clinical system as it traverses acoustic holograms—small artificial objects of different types—within a tank that was filled in with the degassed deionized water. The pressure distribution within the HIFU beam was assessed in multiple planes perpendicular to the beam axis. The ultrasound transducer with the focal length of 14 cm inside the Sonalleve table top (Profound Medical, Mississauga, ON, Canada) generated the focusing ultrasonic beam, which propagated through the water. Each hologram was positioned 3 cm below the focal plane, with precise adjustments of positions and angles for each measurement. Pressure measurements were conducted using the needle hydrophone HNA-0400 (ONDA Corp, Sunnyvale, CA, USA) mounted on a 3D positioning system. The motors of the positioning system were controlled, and pressure values were recorded using a GUI generated in LabVIEW. The displacement step created by the motors on each axis was 0.01 mm. The properties of the holograms were reconstructed, considering the experimental data obtained. Our findings demonstrated that the shape, size, elasticity, and placement of each acoustic hologram significantly influenced the observed field pattern. This work was supported by the German Federal Ministry of Education and Research (“MR-HIFU-Pancreas”, FKZ:13GW0364D).