Abstract
Biomaterials utilized in implantation can be categorized into 4 main categories, as ceramics, polymers, metals and composites. Ceramic-based biomaterials are opted for, particularly in the field of orthopedics. These materials, also named as bioceramics, are usually employed by coating them onto the base material, inasmuch as they are far from the mechanical values of bone. In this study, a hydroxyapatite coating that is fully compatible with human blood plasma was applied on Ti6Al4V alloy through a biomimetic technique using aminoacetic acid-sodium aminoacetate buffer system for the first time in the literature, and examinations related thereto were carried out. The surface of the base material Ti6Al4V alloy was activated with various chemicals. Subsequent to activating the surface, a coating process whereby the base material was kept in simulated body fluid for 24, 48, 72, 96 h was carried out. Ultimate microhardness (indentation) tests were performed to determine the average indentation depths in maximum load, vickers hardness and elasticity modulus of the coatings obtained by using the biomimetic method, while scratch tests were performed to measure the surface bonding strengths of the coating layers. Furthermore, the fracture toughness values of the coating were calculated. The results obtained through the study are evaluated and discussed.
Highlights
Their strength, moldability, and abrasion resistance, as well as their strong metallic bonds, have led to metallic materials having an important place in biomaterials [1]
As a result of this study, a simulated body fluid (SBF) solution biocompatible with human body was prepared by using a biomimetic method in an aminoacetic acid-sodium aminoacetate buffer environment for the first time in literature, and HA coating was performed
HA coating was realized at 37 ◦ C and pH = 7.4 by using the lactic acid/Na-lactate buffer system which was first proposed by Pasinli et al in an environment that is fully compatible with human blood plasma
Summary
Their strength, moldability, and abrasion resistance, as well as their strong metallic bonds, have led to metallic materials having an important place in biomaterials [1]. The biggest disadvantage of metal prostheses in terms of biocompatibility is their being corroded in body fluids containing protein, oxygen and saline solutions [2]. Titanium and its alloys are frequently utilized in intracorporeal implants because of their low propensity for entering into chemical reactions. Ti6Al4V alloy is widely used in the production of implants, such as hip prostheses, bone plates and bone screws in particular in orthopedic applications. The surfaces of these alloys are coated with ceramic-based biomaterials. Their bioactivity and biocompatibility are increased with this process [3]
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