Abstract

Titanium membranes are used for guided bone regeneration in implant therapy. However, as a bioinert material, titanium does not have the ability to accelerate bone formation. Various titanium surface treatments to confer bioactivity have been demonstrated; however, there are concerns about the influence of chemical treatments for thin titanium membranes. This study investigated the influence of surface modifications on the structure of titanium membranes. Titanium membranes of 20 μm thickness were treated with acid or alkali solutions, and we evaluated their surface structure, wettability, thickness, and mechanical strength compared to non-treated membranes. Alkali-treated titanium membranes displayed the formation of nanoscale pore structures on their surfaces, enhanced hydrophilicity, and almost same thickness compared with acid-treated membranes. Furthermore, the tensile strength of alkali-treated membranes was comparable to non-treated membranes. These results suggest that alkali treatment is an appropriate surface modification method for titanium membranes.

Highlights

  • The existence of sufficient bone volume is a factor for successful treatment with dental implants [1].In cases with insufficient bone volume at the implant placement site due to bone absorption or trauma, implant threads can be partially exposed when the implant is placed into the bone tissue, and in these cases, guided bone regeneration (GBR) is applied to augment the bone tissue [2,3]

  • Barrier membranes play a crucial role in GBR, because epithelial tissues recover more quickly than bone, and can invade into the space required for new bone formation and inhibit the process

  • Acid treatment seems to have altered the titanium membrane from a rough surface to a smooth surface, and the acid membrane showed a high contact angle. These results indicated that acid treatment slightly changed the rough surface and reduced the mechanical strength of the titanium membrane

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Summary

Introduction

The existence of sufficient bone volume is a factor for successful treatment with dental implants [1].In cases with insufficient bone volume at the implant placement site due to bone absorption or trauma, implant threads can be partially exposed when the implant is placed into the bone tissue, and in these cases, guided bone regeneration (GBR) is applied to augment the bone tissue [2,3]. Positioning the barrier membrane at the interface between the epithelium and periosteum retains the space required for bone healing. Absorbent membranes such an atelocollagen or polyglycolic acid display excellent operability and do not require removal, and are used as barrier membranes in periodontal therapy. These absorbent membranes are suitable for small bone defects; their application to the grafting of large bone defects is problematic because of their insufficient mechanical strength [4,5]

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