Abstract
We investigated the effects of TNF-α, IFN-γ, IL-10 polymorphisms on viral infections (CMV, BKPyV, HHV-6, EBV) after renal transplantation. IFN-γ+874 A>T (lower IFN production) was associated with CMV disease (p=.039) in patients under mycophenolate-based therapy and graft failure (p=.025). This study underscores the role of IFN-γ+874 SNP in CMV infection.
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