Abstract
Enhanced sensitivity to histamine of children with pertussis has been the basis for speculation regarding similarities of receptor sites among the limited species of mammals said to be hypersensitive, and regarding the desirability of eliminating histamine-sensitizing factor from conventional pertussis vaccines. However, significantly enhanced sensitivity to i.e. injected histamine could not be demonstrated in a group of 6 children with pertussis compared to 4 controls.
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