Investigation Of cTn I, CK-MB, Miyoglobin and D-Dimer Levels at Anemic Dogs Infected Ehrlichiosis

Abstract

Ehrlichiosis is a vector-borne disease that both humans and animals are affected. Multiple tissues and organs are fascinating, and Ehrlichiosis can cause multiple organ failure. In one’s way the known clinical findings and pathogenesis, it is not clear how Ehrlichia is effective and important on myocardial damage and Disseminate Intravascular Coagulation (DIC) profile. Anemia is seen as one of the common clinical conditions in Ehrlichiosis. In this study, it was determined to state the existence of myocardial damage and thromboembolic condition at Ehrlichiosis with the severity of anemia. The animal material of this study consisted of 24 mono-infected, 9 co-infected, and 10 healthy animals. Additionally, animals were separated into mono, co-infected; with anemia profile non-anemic, mild, moderate, and severe anemic, and according to serologic and molecular results; acute infected, ınfected, and active ınfected. CK-MB, cTnI, and Myoglobin levels were calculated in all groups to identify myocardial damage. Accordingly, D-Dimer concentrations were determined to set down the potential of the DIC profile. As a result of the data, D-Dimer levels had a significant increase in mono, co-infected, mild, moderate, severe, and active infected animals (p