INVESTIGATION OF CLINICAL CHARACTERISTICS OF TRICHOMONIASIS AND METRONIDAZOLE SUSCEPTIBILITY OF TRICHOMONAS STRAINS ISOLATED FROM THUA THIEN HUE

Abstract

Trichomoniasis is one of the most common sexual transmitted diseases with changable clinical features. The prevalence of metronidazole resistance was different among the studies in the literature. Objectives: The aim of this study was to describe the characteristics of T. vaginalis infection and to investigate the susceptibility with metronidazole of T. vaginalis strains. Materials and methods: A cross-sectional and experimental studies were performed using the interview, the direct examination, the culture of T. vaginalis in Diamond medium, and the investigation of the metronidazole susceptibility by broth microdilution method. Results: The rate of trichomoniasis was 0.37%, in which 16.7% of patients with single status, and 76.7% of those who did not use any contraceptive methods. The common symptoms were increased vaginal discharge, itching and pain (50%); opalescent vaginal discharge (33.3%), The rate of women with asymptomatic T. vaginalis was 26.7%. The percentage of metronidazole susceptibility, intermediate and resistance to metronidazole were 73.1%, 19.2% and 7.7%, respectively. Conclusions: The study showed that T. vaginalis infection had a low rate, high proportion of asymptomatic patients and 7.7% of patients were resistant to metronidazole. Key words: T. vaginalis, metronidazole, resistant