Investigation of clinical and pathological findings due to anatomical localisation in patients with colorectal cancer.

Abstract

We classified anatomical localisation tumours of patients diagnosed with colorectal cancer and undergoing surgery as right and left colon and we aimed to determine how this funding affects the prognosis of the disease and survival times. In our study, 521 patients who applied to the general surgery outpatient clinic of İnönü University Turgut Özal Medical Center 19.06.2009 and 15.08.2019 between dates and operated with a diagnosis of colorectal cancer files were reviewed retrospectively. The patients' data were compared as age, gender, genetic predisposition, stage of tumour, distance to surgical margins (distal and radial), size, number of lymph nodes, metastasising organs, colon macroscopic features, chemotherapy and survival. In total, 42.6% of the patients were female and 57.4% were male. The average age of all patients is 59.79. The average age of women was 60.39 ± 1.023 and the average age of male patients was 59.35 ± 1.800. The anatomical regions where colorectal cancer was most common were rectum, colon sigmoideum and caecum. 40.5% of the patients had a tumour located in the right colon, while 59.5% had a tumour in the left colon. When the distal surgical margin (P = .002), proximal surgical margin (P = .001), tumour size (P = .001) and the number of removed lymph nodes (P = .002) were evaluated in these patients. The mean survival in the right colon was 71.499 ± 3.589 months and in the left colon was 71.121 ± 2.953 months. The longest survival was 76.856 ± 6.117 months in colon ascendens, while the shortest survival was calculated as 57.399 ± 4.671 months in flexura coli dextra. We are thinking that in colorectal cancer, the anatomical localisation of the tumour can hold an important place to determine the clinical differences such as, the disease symptoms, course, treatment options and survival status.