Abstract
Opioid peptides have been implicated in many biological processes acting as hormones, neurohormones or neurotransmitters. The aim of this research was to investigate effect of endurance training on plasma beta endorphin (BA) changes in active and sedentary girls. 12 healthy physical education students as active group (n = 12, active group with, 21.6 ± 0.6 year age, 162.25 ± 3.68 cm in height, and 54.13 ± 6.35 kg, weight) and 12 healthy non physical education as sedentary group (n = 12, sedentary group, age 20.55 ± 0.69 year, high, 161.40 ± 3.14 cm, weight, 59.25 ± 4.45 kg) requited. Subjects entered the study on their usual diet and after familiarization with training protocol, Bruce test (treadmill test) as aerobic test applied. The blood sample was collected before and after training in both groups. Beta-endorphin concentration was determined by radioimmunoassay kits. The analyses and data processing showed that there is no significant difference within active (0.77 ± 0.1 pmol/l) and sedentary group (0.82 ± 0.01 pmol/l) in basal BE at rest. The BE levels after endurance training in active group and sedentary group increase respectively (0.83 ± 0.09 pmol/l), (compared with basal) however, significant difference was found between pre and post test group in active group (P > 0.05). In this research, BE secretion increased in response to endurance exercise both in active and sedentary girls.
Highlights
Endogenous opioid peptides constitute a flexible and widespread regulatory modulatory system
Opioid peptides have been implicated in many biological processes acting as hormones, neurohormones or neurotransmitters
Met-enkephalin is found in the blood plasma and in a relatively high concentration in comparison with other opioid peptides (Angelo et al, 2001)
Summary
Endogenous opioid peptides constitute a flexible and widespread regulatory modulatory system. Opioid peptides have been implicated in many biological processes acting as hormones, neurohormones or neurotransmitters. Their influence is mediated by specific opioid receptors. In this tissue methione and leucine enkephalins (met- and leu-enkephalins) are purified and characterized. Met-enkephalin is found in the blood plasma and in a relatively high concentration in comparison with other opioid peptides (Angelo et al, 2001). An extremely high concentration of enkephalins is co-localized and co-released with catecholamines in adrenal medulla. In this connection the met-enkephalin concentrations in the adrenal vein is higher than in other parts of the circulation. The majority of the circulation met-enkephalin originnates in the sympathetic nervous system (Bender et al, 2007; Pierce et al, 1993)
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