Abstract

Background HIV integrase (IN) plays important roles at several steps, including viral DNA nuclear import, targeting viral DNA to host chromatin and integration. Identification of novel inhibitors of HIV Integrase has emerged as promising antiviral agents for the treatment of HIV/AIDS. Present work is to investigation of anti-HIV activity and HIV integrase inhibitory activity of various extracts of polyherbal formulation BH.

Highlights

  • HIV integrase (IN) plays important roles at several steps, including viral DNA nuclear import, targeting viral DNA to host chromatin and integration

  • Identification of novel inhibitors of HIV Integrase has emerged as promising antiviral agents for the treatment of HIV/AIDS

  • Present work is to investigation of anti-HIV activity and HIV integrase inhibitory activity of various extracts of polyherbal formulation BH

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Summary

Open Access

Investigation of anti-HIV activity, cytotoxicity and HIV integrase inhibitory activity of polyherbal formulation BH extracts. S Balraj1*, P Selvam[2], Y Pommier[3], M Metifiot[3], M Christophe[3], C Pannecouque[4], E De Clercq[4]. From 2nd International Science Symposium on HIV and Infectious Diseases (HIV SCIENCE 2014) Chennai, India. From 2nd International Science Symposium on HIV and Infectious Diseases (HIV SCIENCE 2014) Chennai, India. 30 January - 1 February 2014

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