Abstract
Objective To investigate the level of anxiety and depression and its influencing factors in patients with intravesical perfusion chemotherapy. Methods Totally 148 patients with intravesical perfusion chemotherapy were investigated using the Hospital Anxiety and Depression Scale, Self-Perceived Burden Scale and Social Support Rating Scale. Results Among the patients, 14.2% (21/148) and 20.3% (30/148) of them expressed respectively their anxiety and depression, and the incidence of anxiety and depression was significantly correlated with the self-perceived burden, social support and its dimensions (P<0.05), in addition to the influence of the course time(P=0.002), religion(P=0.040), and the functional status of the caregiver(P=0.009). Conclusions The incidence rate of anxiety and depression in patients with intravesical perfusion chemotherapy is still to be further controlled. Nursing staff should pay attention to patients' self-perceived burden, and play an important role in social support in order to reduce the incidence of anxiety and depression. Key words: Urinary bladder neoplasms; Drug therapy; Chemotherapy, cancer, regional perfusion; Anxiety; Depression
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