Abstract
Cancer has been a leading cause of death worldwide, and the role of obesity in cancer has become an alarming issue in recent years. Although the direct mechanism between obesity and cancer remains incompletely understood, the correlation between the carcinogenic disorders caused by obesity and the substantial number of obese patients shows the connection between the two. The chemicals produced from cells during inflammation, known as reactive oxygen species, can damage the DNA of normal cells, potentially causing cancer. Diseases associated with obesity such as Type II diabetes can also lead to inflammation from insulin resistance based on the presence of inflammation markers. This paper reviews connections between obesity and cancer by analyzing peer-reviewed literature over the past 20 years investigating with a focus on the mechanism of the carcinogenic disorders caused by obesity.
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