Investigating the potential use of (ZnO)60 nanoparticle as drug delivery system for chloroquine, hydroxychloroquine, favipiravir, and remdesivir

Abstract

This study delves into the potential use of (ZnO)60 nanoparticle (NP) as a drug delivery system for chloroquine (CQ), hydroxychloroquine (HC), favipiravir (F), and remdesivir (R). The interaction mechanisms between (ZnO)60 NP and these drug molecules are explored using advanced computational methods. A comprehensive evaluation of the structural, electronic, and reactivity properties of the drug molecules during their interaction with (ZnO)60 NP is conducted. The findings reveal that (ZnO)60 NP exhibit stable and favorable interactions with CQ, HC, F, and R, positioning them as promising candidates for targeted drug delivery. This research significantly contributes to the development of improved therapeutic interventions and provides valuable insights into the field of drug delivery systems.