Abstract
The discovery of unique autoantibodies has informed and altered our approach to the diagnosis and management of the inflammatory myopathies. This study reports the initial clinical experience of use of the Extended Myositis Antibody (EMA) panel in the largest university teaching hospital in Ireland. We conducted a retrospective review of all patients who had serum samples tested for myositis specific antibodies and myositis associated antibodies from April 2014 to March 2015. A positive EMA panel was of significant clinical utility in facilitating decisions on appropriate investigations, and need for onward referral to other physicians. Furthermore, this paper highlights the diversity of possible presentations of idiopathic inflammatory myopathy with subsequent need for multi-speciality involvement, and serves to heighten awareness among clinicians of the diagnostic use of extended myositis antibody testing in these cases.
Highlights
Cork University Hospital (CUH) is the largest university teaching hospital in Ireland, and is a multi-specialty tertiary referral centre drafting the work and revising it critically for important intellectual content, final approval of the version to be published, agreement to be accountable for all aspects of the work in
A c positive Extended Myositis Antibody (EMA) panel was of significant clinical utility in facilitating decisions on appron priate investigations, and need for onward o referral to other physicians
Autoimmune Inflammatory Myopathies immunoblot was performed at University Hospital Galway
Summary
This study c reports the initial clinical experience of use r of the Extended Myositis Antibody (EMA) e panel in the largest university teaching hospital in Ireland. A c positive EMA panel was of significant clinical utility in facilitating decisions on appron priate investigations, and need for onward o referral to other physicians. N ble presentations of idiopathic inflammatory myopathy with subsequent need for multi-speciality involvement, and serves to heighten awareness among clinicians of the diagnostic use of extended myositis antibody testing in these cases.
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