Abstract
This report demonstrates the presence of the immunoreactive enzyme nitric oxide (NO) synthase in the molluscan hemocytes of Viviparus ater. Bacterial elimination by the hemocytes occurs through phagocytosis and the nitric oxide (NO) system. These processes are correlated, and the hemocytes activate phagocytosis before the NO defence response. This behaviour could be explained by the fact that, as in vertebrate macrophages, NO synthase can also be induced in invertebrate hemocytes. Indeed, in the bacteria-activated hemocytes there is an increase of NO synthase in comparison to controls. Moreover, the same behaviour is also seen in the NADPH diaphorase activity. These findings suggest a pivotal role of the NO system in defence mechanisms, and indicate that, as with phagocytosis, this system developed very early in the course of evolution.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
