Abstract
The risk-benefit ratio of inverse ratio ventilation in the treatment of acute lung injury is still controversial. The new method, airway pressure release ventilation, is conceptually similar to pressure-controlled inverse ratio ventilation. However, in contrast to pressure-controlled inverse ratio ventilation, spontaneous breathing is unrestricted during airway pressure release ventilation. This review discusses the results of experimental and clinical trials of inverse ratio ventilation and airway pressure release ventilation. Although no final recommandation can be made for the clinical use of inverse ratio ventilation, airway pressure release ventilation offers attractive advantages over controlled ventilatory modes by the combination of spontaneous ventilation and mechanical ventilatory support.
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