Abstract
Invasive pulmonary aspergillosis (IPA) is a rare disease occurring mainly in immunocompromised patients. Currently, there is a steady increase in the number of patients with oncohematological diseases, autoimmune pathology, requiring new highly effective immunosuppressive therapy, however, HIV infection remains one of the main reasons for the development of immunosuppression. Despite the progress made in studying issues related to HIV infection, many problems, especially in relation to the course of this disease and secondary infections in children, remain unresolved. One of them is invasive mycosis, including PLA. The article presents a clinical observation of IPA in a 7-year-old patient with newly diagnosed HIV infection, demonstrates the difficulties of diagnosing and treating such conditions.
Highlights
Invasive pulmonary aspergillosis (IPA) is a rare disease occurring mainly in immunocompromised patients
There is a steady increase in the number of patients with oncohematological diseases, autoimmune pathology, requiring new highly effective immunosuppressive therapy, HIV infection remains one of the main reasons for the development of immunosuppression
Despite the progress made in studying issues related to HIV infection, many problems, especially in relation to the course of this disease and secondary infections in children, remain unresolved
Summary
Invasive pulmonary aspergillosis (IPA) is a rare disease occurring mainly in immunocompromised patients. ВИЧ-инфекция и иммуносупрессии, 2021 г., Том 13, No 4 Небольшое количество наблюдений ИЛА у пациентов детского возраста с ВИЧ-инфекцией приводит к медленному накоплению знаний о данной патологии, что препятствует ранней ее диагностике и эффективному лечению. ИЛА требует проведения дифференциальной диагностики с широким кругом заболеваний, в том числе и с рядом оппортунистических инфекций, а селективность и низкая доступность методов этиологической верификации диагноза серьезно затрудняют этот процесс.
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