Abstract

Invasive meningococcal disease incidence in England declined from 1.93/100,000 persons (1,016 cases) in 2010–11 to 0.95/100,000 (530 cases) in 2018–19 and 0.74/100,000 in 2019–20 (419 cases). During national lockdown for the coronavirus disease pandemic (April–August 2020), incidence was 75% lower than during April–August 2019.

Highlights

  • Neisseria meningitidis is a major global cause of bacterial meningitis and septicemia (1)

  • We report invasive meningococcal disease (IMD) incidence in England during 2011–2020, including the impact of a national lockdown to control the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

  • Adolescent MenACWY and infant 4CMenB immunization programs in 2015 led to additional annual declines in IMD incidence, to 0.95 cases /100,000 population (530 cases) in 2018–19

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Summary

Introduction

Neisseria meningitidis is a major global cause of bacterial meningitis and septicemia (1). We report IMD incidence in England during 2011–2020, including the impact of a national lockdown to control the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). IMD incidence was highest, 1.93 cases/100,000 population (1,016 total cases), during the 2010–11 academic year (September–August) and declined to 1.15 cases /100,000 population for 2013–14 (617 cases) before increasing to 1.51 cases /100,000 population (825 cases) in 2015–16 (Figure).

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