Abstract

BackgroundCystic hypersecretory carcinoma is a rare subtype of breast cancer. It is a member of cystic hypersecretory lesions, which include a series of pathological disease lineages: cystic hypersecretory hyperplasia (CHH), CHH with atypia, cystic hypersecretory carcinoma (CHC) and invasive CHC. It was found that most cystic hypersecretion lesions were in situ carcinoma, and only 19 cases of invasive cystic hypersecretion carcinoma were reported.Case presentationWe are reporting a case of a 63-year-old female who had a lump in her left breast for 3 years. A modified radical mastectomy was done and morphological diagnosis of invasive CHC with axillary node metastasis was made.ConclusionsOwing to a smaller number of reported cases, little is known about the biological behavior, prognosis and molecular study of cystic hypersecretion lesions. Therefore, more cases with follow-up data are needed to reveal the biological behavior of this rare tumor.

Highlights

  • Cystic hypersecretory lesions of the breast have a spectrum of morphological features ranging from clearly benign (CHH), cystic hypersecretory hyperplasia (CHH) with atypia, cystic hypersecretory carcinoma (CHC) to invasive CHC [1]

  • Owing to a smaller number of reported cases, little is known about the biological behavior, prognosis and molecular study of cystic hypersecretion lesions

  • Cystic hypersecretory lesions of the breast have a spectrum of morphological features ranging from clearly benign (CHH), CHH with atypia, cystic hypersecretory carcinoma (CHC) to invasive CHC [1]

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Summary

Conclusions

Owing to a smaller number of reported cases, little is known about the biological behavior, prognosis and molecular study of cystic hypersecretion lesions.

Introduction
Discussion
DCIS with comedo necrosis
Secretory carcinoma
Conclusion
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