Invasive capacity of differentiated thyroid carcinoma in pediatric and adolescent patients

Abstract

To summarize the invasion features of differentiated thyroid carcinoma (DTC) in pediatric and adolescent patients. The clinical data of 32 DTC cases (≤18 years old) were retrospectively analyzed for the invasive capacity of DTC in terms of age and gender. Bilateral (P=0.023), multifoci (P=0.037), and extrathyroid invasions (P=0.041) were more often in patients younger than 12 years old. DTC in pediatric and adolescent patients tend to have a more aggressive pattern, especially in patients younger than 12 years.