Invasive Aspergillosis in an Immunocompetent Asian Teenager

Abstract

Purpose: To report a case of invasive Sino-orbital aspergillosis in an Immunocompetent Asian teenager Method: Case Report Result: An immunocompetent Asian teenager with no comorbidities presented with a unilateral orbital proptosis with orbital cellulitis-like symptoms was unresponsive to medical therapy. Findings on computed tomography demonstrated a fairly homogenous mass occupying the entire left maxillary sinus, with erosion of the orbital floor and medial wall to invade the ethmoids and the orbit. Excision biopsy of the mass showed fungal elements with tissue invasion and granulomatous reactions. Treatment included excision of the mass and systemic antifungals. During the course of treatment, however, the patient lost vision on the affected eye, which did not improve even after excision of mass and treatment of the infection Conclusion: Clinicians should be aware of the possibility of having a fungal infection mimicking other infections and tumors in immunocompetent host since prompt treatment could possibly save the vision, and, in the long run, the patient’s life.