Abstract
Blood cultures are among the most frequently ordered and clinically important tests performed in clinical microbiology laboratories. Recognizing this importance, manufacturers have produced a wide variety of commercial blood culture products that may be evaluated in controlled clinical trials. Therefore, clinical microbiologists must be able to discern those studies with useful data and valid conclusions from those that are scientifically invalid. This article reviews blood culture terminology used in the blood culture literature and briefly reviews some of the critical factors in designing valid clinical blood culture evaluations.
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