Abstract
Neuroimmunology first emerged as an independent discipline early in the 1980s. Initially, the brain was regarded as an immune-privileged site, as the blood-brain barrier prevented immune access. To our benefit, the field of immunology evolved significantly, and, 40 years from its inception, neuroimmunology has proven that these two systems are closely intertwined. Over the years, we have garnered a vast improvement in the understanding of the intricate crosstalk and mechanistic insights between the immune system and the central nervous system.This issue of Neurosurgical Focus on neuroimmunology aims to describe the most recent developments in immunology
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