Abstract

Drosophila melanogaster, known colloquially as the fruit fly, remains one of the most commonly used model organisms for biomedical science.[...].

Highlights

  • Drosophila—A Model System for Developmental BiologyReceived: September 2017; Accepted: September 2017; Published: 20 September 2017Keywords: Drosophila; model organisms; development; geneticsDrosophila melanogaster, known colloquially as the fruit fly, remains one of the most commonly used model organisms for biomedical science

  • Any gene or even allele related to human disease can be studied in flies

  • As research budgets shrink in real terms, it is easy to overlook basic research in such an abstract and annoying animal as the fruit fly

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Summary

Introduction

Drosophila—A Model System for Developmental BiologyReceived: September 2017; Accepted: September 2017; Published: 20 September 2017Drosophila melanogaster, known colloquially as the fruit fly, remains one of the most commonly used model organisms for biomedical science. 2017, 5, 9 an exon swapping approach [9]. These, in conjunction with CRISPR/Cas9 knockout/knockin and overexpression strategies [10], allow the inactivation, tagging, and overexpression of any gene in the genome within weeks of starting a project.

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