Introduction. Biologics in spine surgery.

Abstract

In this issue, we explore the role of biologics in spinal fusion. The treatment of spinal disorders has been revolutionized over the last 25 years with the introduction of biologics to enhance bone density in preparation for surgery and to promote bony arthrodesis in spinal fusion surgery. The use of these products has become even more important in the era of minimally invasive spinal surgery, where bone graft surface area for fusion is at a premium.Use of osteobiologics for bone fusion is known to promote migration, differentiation, cellular division, or replacement of bone-forming cells, ultimately resulting in