Introducing a chemical-based gel dosimeter for radiation measurement

Abstract

Radiation dosimetry plays important role in the reproducibility of radiobiological experiments & the replicability of results and so the successful radiotherapy treatment. There exist several methods to measure doses such as chemical and gel dosimetry. In this study, a novel dosimeter was evaluated capable of reading with both MRI & spectrofluorometer.Trimesic acid with different concentrations and pH was mixed with a matrix of gelatin & acrylamide gel and were poured at different vials to be exposed at different doses up to 200 cGy at two temperature of 4 °C and 25 °C and the readings were used to extract calibration curves for MRI with different TE2s & spectrofluorometer methods which Pearson correlation coefficient (R2) for each method & their interaction were used to find out the best conditions.The results were obtained as dosimeter calibration curves with related R2 of two different reading methods of MRI & spectroflourimetry in dose range of 0–200 cGy. The R2 was a measure to compare different experimental groups & also an interaction between MRI and spectroflourimetry R2s was considered to determine which combination results to a better two reading, simultaneously.It was showed that in the considered dose range, at lower temperature of 4 °C, weak acidity & lower concentration of Trimesic acid, the proposed dosimeter seems to be a two reading or hybrid dosimeter.