Abstract

AbstractPurpose To report our visual outcomes in a series of five cases of classic choroidal neovascularization (CNV) associated with choroidal nevus which were treated with intravitreal ranibizumab injections.Methods Interventional case series. Each patient underwent a complete ophthalmic evaluation, including fluorescein angiography and spectral domain optical coherence tomography (SD‐OCT). Data were retrospectively analyzed to evaluate both clinical and anatomical results following intravitreal treatment.Results The CNV was juxtafoveolar in four cases and extrafoveolar in one case. Intravitreal ranibizumab therapy was used in all five cases by using 2‐5 injections (mean 3.4 injections). Moreover, two cases required other therapies: photodynamic therapy (PDT) in one case of juxtafoveolar CNV and laser photocoagulation in a case of extrafoveolar CNV. After a mean follow‐up of 18.6 months, final best‐corrected visual acuity (BCVA) increased in two cases, decreased in two cases and remained stable in one case. There were no adverse effects associated with ranibizumab injections. All choroidal nevi remained stable, showing no signs of malignancy.Conclusion Intravitreal ranibizumab injections appear to be a safe and effective treatment modality for CNV associated with choroidal nevus.

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