Intravitreal dexamethasone implant for the treatment of cystoid macular oedema associated with acute retinal necrosis.

Parthopratim Dutta Majumder,Ahmed Magdy Bedda,Asra Ambreen,Jyotirmay Biswas,Rowayda Amin,Zahedur Rahman Pannu

doi:10.1186/s12348-016-0116-x

Parthopratim Dutta Majumder, Ahmed Magdy Bedda + Show 4 more

Open Access

https://doi.org/10.1186/s12348-016-0116-x

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Abstract

BackgroundAcute retinal necrosis is a rare but devastating ocular condition. We report two cases of acute retinal necrosis in immunocompetent patients, complicated by cystoid macular oedema and treated with intravitreal dexamethasone (OZURDEX®) implant.ResultsTwo patients diagnosed with acute retinal necrosis were treated with intravenous acyclovir. Both of them developed cystoid macular oedema following resolution of viral retinitis. Ocular condition of the first patient was further complicated by central serous chorioretinopathy. Under unavoidable circumstances, cystoid macular oedema in both the patients was treated with intravitreal dexamethasone implant with great caution. Resolution of cystoid macular oedema without recurrence of viral retinitis was noted in the long-term follow-up.ConclusionsFindings of the case report should be interpreted cautiously, and extreme caution should be exercised prior deciding the management with a corticosteroid implant in patients with viral retinitis. However, intravitreal dexamethasone implant can be a useful option in selected patients with cystoid macular oedema in acute retinal necrosis.

Highlights

Acute retinal necrosis is a rare but devastating ocular condition
We report two cases of Acute retinal necrosis (ARN) in immunocompetent patients, complicated by cystoid macular oedema and treated with intravitreal dexamethasone (OZURDEX®) implant
Fundus examination revealed cystoid macular oedema (CME) in the left eye, which was confirmed in optical coherence tomography (OCT) with thickness of 422 μ

Summary

Results

Two patients diagnosed with acute retinal necrosis were treated with intravenous acyclovir. Both of them developed cystoid macular oedema following resolution of viral retinitis. Ocular condition of the first patient was further complicated by central serous chorioretinopathy. Cystoid macular oedema in both the patients was treated with intravitreal dexamethasone implant with great caution. Resolution of cystoid macular oedema without recurrence of viral retinitis was noted in the long-term follow-up

Conclusions

Introduction

Discussion