Abstract

BackgroundPostoperative deaths and neurological injury have resulted from hyponatraemia associated with the use of hypotonic saline solutions following surgery. We aimed to determine the rates and types of intravenous fluids being prescribed postoperatively for children in the UK.MethodsA questionnaire was sent to members of the British Association of Paediatric Surgeons (BAPS) and Association of Paediatric Anaesthetists of Great Britain and Ireland (APAGBI) based at UK paediatric centres. Respondents were asked to prescribe postoperative fluids for scenarios involving children of different ages. The study period was between May 2006 and November 2006.ResultsThe most frequently used solution was sodium chloride 0.45% with glucose 5% although one quarter of respondents still used sodium chloride 0.18% with glucose 4%. Isotonic fluids were used by 41% of anaesthetists and 9.8% of surgeons for the older child, but fewer for infants. Standard maintenance rates or greater were prescribed by over 80% of respondents.ConclusionMost doctors said they would prescribe hypotonic fluids at volumes equal to or greater than traditional maintenance rates at the time of the survey. A survey to describe practice since publication of National Patient Safety Agency (NPSA) recommendations is required.

Highlights

  • Postoperative deaths and neurological injury have resulted from hyponatraemia associated with the use of hypotonic saline solutions following surgery

  • Hyponatraemia occurs as the hypotonic saline is a source of free water, which cannot be excreted if Anti Diuretic Hormone (ADH) levels are elevated due to the surgical stress response

  • A postal questionnaire was sent to members of the British Association of Paediatric Surgeons (BAPS) and APAGBI working at tertiary referral centres in the UK

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Summary

Introduction

Postoperative deaths and neurological injury have resulted from hyponatraemia associated with the use of hypotonic saline solutions following surgery. We aimed to determine the rates and types of intravenous fluids being prescribed postoperatively for children in the UK. The danger of hyponatraemia is cerebral oedema resulting in seizures, neurological deterioration and sometimes in tentorial herniation and death. This can cause permanent neurological injury and death [5]. Hyponatraemia occurs as the hypotonic saline is a source of free water, which cannot be excreted if Anti Diuretic Hormone (ADH) levels are elevated due to the surgical stress response. The mechanism of action of ADH is to impair free water excretion

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