Intravenous paracetamol infusion and tramadol as agents for post operative pain relief in urosurgical patient: A randomized control trial

Abstract

Analgesia is one of the most important consideration in perioperative setting as it determines the recovery and discharge of a patient. Among the drugs used for analgesia, non steroidal anti-inflammatory drugs and opioids are the most commonly used ones in the current scenario. The aim of this study was to compare the efficacy of intravenous (IV) paracetamol and IV tramadol in alienating pain postoperatively. 100 adult patients of ASA grade I & II in the age group of 25-55 years were randomized into two groups of 50 patients , scheduled for elective urosurgical procedures and were administered IV paracetamol and IV tramadol 30 minutes before the completion of surgery for postoperative analgesia and assessment was done with visual analog scale (VAS)score. In the present study, both the drugs showed effective pain relief. The onset of analgesia is faster in tramadol group. In paracetamol group, the onset of analgesia was slightly delayed but pain scores significantly decreased after 60 min, and this was observed up to 6 h with a statistically significant decrease in post operative nausea vomiting( PONV )with paracetamol group .