Abstract

Lidocaine’s versatility is seen in the many routes by which it can be administered. It is given topically or by infiltration for procedural pain, such as for venous punctures and laceration repairs, and is available in a topical patch formulation for peripheral types of pain, such as postherpetic neuralgia. Lidocaine may be delivered epidurally and by single injection or continuous peripheral nerve block infusion. It has been administered for many years by the intravenous (IV) route for regional anesthesia (Bier block) for surgical procedures and increasingly by brief IV infusion as a third-line option for the treatment of refractory neuropathic and postoperative pain.

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