Abstract

Chronic kidney disease (CKD), diabetes mellitus, older age, acute coronary syndrome, and cardiogenic shock are the common predisposing factors for contrast-induced acute kidney injury (CI-AKI) after percutaneous coronary intervention (PCI). Apart from intravenous normal saline administration, other measures to prevent CI-AKI have not been consistently beneficial. More recently, intravascular ultrasound (IVUS)-guided zero-contrast PCI has emerged as an important method to prevent CI-AKI in experienced centers. Technical expertise in complex PCI and meticulous analysis of IVUS are required for this procedure. In this review, the authors have described the basic details of the steps involved in this technique. The authors believe that clinical implementation of this technique has the potential for mortality benefit in patients who are at high risk of CI-AKI.

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