Abstract
Intravascular papillary endothelial hyperplasia or Masson's tumor is a rare reactive disease of vascular origin characterized by exuberant proliferation of endothelial cells notably occurring within blood vessels of head, neck, and extremities. The importance of this entity is its ability to mimic a variety of diseases both benign and malignant in the orofacial region. Here, we present a case of Masson's tumor within the masseter muscle in a 40-year-old female with emphasis on the sequential investigative procedures performed to diagnose this entity.
Highlights
Vascular tumors in the oral region have been traditionally described as hamartomas or malformations rather than as true neoplasms
Stout stated that a vascular tumor, in contrast to a hamartoma, contained more endothelial cells than was necessary to line the lumina
Intravascular papillary endothelial hyperplasia (IPEH) is a benign, nonspecific, vascular lesion consisting of reactive proliferation of the endothelial cells that arise in organizing thrombus [2]
Summary
Vascular tumors in the oral region have been traditionally described as hamartomas or malformations rather than as true neoplasms. Stout stated that a vascular tumor, in contrast to a hamartoma, contained more endothelial cells than was necessary to line the lumina. Vascular lesions have a tumor-like appearance, due to endothelial proliferation in vessels and enlargement of vessels with secondary reactive change [1]. Intravascular papillary endothelial hyperplasia (IPEH) is a benign, nonspecific, vascular lesion consisting of reactive proliferation of the endothelial cells that arise in organizing thrombus [2]. It comprises approximately 2% of the vascular tumors of the skin and subcutaneous tissue [3]
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