Intravascular large B-cell lymphoma with involvement of the abdominal subcutis: a case report and literature review

Abstract

Intravascular large B-cell lymphoma (IVLBCL) is a rare subtype of diffuse large B-cell lymphoma (DLBCL). It commonly presents with a variety of symptoms due to occlusion of small vessels by tumor cells in different organ systems. Clinically patients may present with generalized symptoms such as fever and malaise. In western patients, there is a 'cutaneous variant' of IVLBCL, which demonstrates cutaneous involvement only. However, Asian patients show hemophagocytosis, which is typical of the 'Asian variant'. Here we report a case of IVLBCL in a Chinese individual who presented with a huge mass in the subcutis of the abdomen.