Intravascular Large B-cell Lymphoma

Abstract

Intravascular large B-cell lymphoma is an extranodal large B-cell lymphoma characterized by the selective growth of tumor cells in small vessels. It is often difficult to diagnose because of its various and non-specific manifestations. A key to diagnosis is an understanding of how to suspect this disease and performing tissue diagnoses including random skin biopsy. Due to advances in treatment, the importance of early diagnosis is increasing. However, as the pathogenesis and manifestations of the disease are still unclear, additional knowledge is needed.