Abstract
There are a number of disadvantages inherent in all oral hormonal contraceptives: need for daily administration, fluctuations of hormone levels throughout the day, metabolism in the gastrointestinal tract, the effect of the first passage through the liver. All this became a prerequisite to the creation of prolonged oral hormonal methods of contraception, which would be devoid of these shortcomings. One of such method of hormonal contraception is intravaginal hormonal system. The aim was to determine the safety and efficacy of its use in women of reproductive age with overweight. 43 women were included. State of lipid metabolism, changes of the hemostatic system, blood pressure and weight fluctuations in the past 6 months of using intravaginal hormonal contraceptive system were studied. Results. It is established that hormonal intravaginal contraceptive ring gives minimal metabolic effects. Conclusion. This suggests that this ring can be used successfully in patients with excessive body mass, because there is no effect of the ring on hemostasis, lipid metabolism and body weight.
Highlights
Існує ряд недоліків, що властиві всім пероральним гормональним контрацептивам: необхідність щоденного приймання, коливання рівня гормонів протягом доби, метаболізм у шлунково-кишковому тракті, ефект первинного проходження через печінку
There are a number of disadvantages inherent in all oral hormonal contraceptives: need for daily administration, fluctuations of hormone levels throughout the day, metabolism in the gastrointestinal tract, the effect of the first passage through the liver
All this became a prerequisite to the creation of prolonged oral hormonal methods of contraception, which would be devoid of these shortcomings
Summary
Ключові слова: контрацепція, інтравагінальна гормональна система, надмірна вага. Існує ряд недоліків, що властиві всім пероральним гормональним контрацептивам: необхідність щоденного приймання, коливання рівня гормонів протягом доби, метаболізм у шлунково-кишковому тракті, ефект первинного проходження через печінку. Одним із таких методів гормональної контрацепції є інтравагінальна гормональна система. Интравагинальная гормональная контрацепция у женщин репродуктивного возраста с избыточной массой тела И. There are a number of disadvantages inherent in all oral hormonal contraceptives: need for daily administration, fluctuations of hormone levels throughout the day, metabolism in the gastrointestinal tract, the effect of the first passage through the liver. All this became a prerequisite to the creation of prolonged oral hormonal methods of contraception, which would be devoid of these shortcomings. Changes of the hemostatic system, blood pressure and weight fluctuations in the past 6 months of using intravaginal hormonal contraceptive system were studied
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