Abstract

This paper studies the risk of intrauterine compromise in the fetuses with intrauterine growth restriction (IUGR) using support vector machines (SVM). A structured and globally optimized SVM system may be preferable procedure in the identification of IUGR fetus at risk. The IUGR risk is estimated in two stages: In the first stage, noninvasive Doppler pulsatility index (PI) and resistance index (RI) of umbilical artery (UA), middle cerebral artery (MCA) and ductus venosus (DV), and amniotic fluid index (AFI) are retrospectively analyzed and the Doppler indices are applied to the SVM system to make a diagnosis decision on the fetal well being as “reactive” or “nonreactive and/or fetal distress (FD)” on the nonstress test (NST) (training data). In the second stage (testing data), the decision is validated by the NST (target value). Experiments are performed in retrospective clinical situation. Forty-four preterm with IUGR and without IUGR pregnancies before 34 weeks gestation are considered. Also, the nonparametric Bayes-risk decision rule, k-nearest neighbor (k-NN), is used for comparison. It is observed that the SVM system is proven to be useful in predicting the expected risk in IUGR cases in the small population study. Also, the PI and RI values of UA, MCA and DV are effective in distinguishing IUGR cases at risk.

Highlights

  • Intrauterin growth restriction (IUGR) is a fetal growth disorder which is associated with fetal hypoxia and increased perinatal morbidity / mortality [1,2,3,4,5]

  • The data given is extracted from a small population, support vector machines (SVM) s are still capable of extracting information with 70% of a sensitivity, 81.7% of specificity with pulsatility index (PI) indices of umbilical artery (UA), middle cerebral artery (MCA) and ductus venosus (DV)

  • The effectiveness of the system is supported by 71.8 % positive predictive value (PPV) on diagnosis of hypoxia suspicion

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Summary

1.INTRODUCTION

Intrauterin growth restriction (IUGR) is a fetal growth disorder which is associated with fetal hypoxia and increased perinatal morbidity / mortality [1,2,3,4,5]. Varol fetal middle cerebral artery (MCA), appearance of retrograde flow pattern in ductus venosus (DV), severe oligohydramnios (AFI

Expected and Empirical Classification Risk
IUGR Risk Decision based on SVM
RESULTS
DISCUSSION AND CONCLUSION
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