Abstract
In a case of intractable cancer pain in spite of high dose of opioids, intrathecal administration of morphine is often selected. We implant intrathecal(IT) catheter insertion with subcutaneous port for the route of morphine and local anesthetic infusion (no implantable pumps are available in Japan). In 49 patients, average pain score decreased from 7.09 to 2.31, given opioid decreased from 705mg/day(oral) to 10.0mg/day(IT). Additionally, median adjuvant drug numbers had decreased from 3drugs to none.
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