Abstract
Neurorehabilitation of patients with spinal cord injury and severe muscle spasticity have always been one of the most challenging tasks for neurologists. Muscle spasticity significantly impairs patients’ quality of life and is often resistant to pharmacotherapy. Over the last 10 years, intrathecal baclofen therapy has become the most effective treatment for spasticity in Russia. In this study, we tried to systematize the data on intrathecal baclofen therapy in patients with spinal cord injury complicated by spasticity and to evaluate their treatment outcomes, as well as the incidence of adverse events. Our findings will ultimately help to clarify the need for intrathecal baclofen therapy in routine clinical practice.
Highlights
Intrathecal baclofen therapy in the management of drug-resistant muscle spasticity in patients with traumatic spinal cord injury
We tried to systematize the data on intrathecal baclofen therapy in patients with spinal cord injury complicated by spasticity and to evaluate their treatment outcomes, as well as the incidence of adverse events
Our findings will help to clarify the need for intrathecal baclofen therapy in routine clinical practice
Summary
D. Intrathecal baclofen therapy in the management of drug-resistant muscle spasticity in patients with traumatic spinal cord injury. Цель исследования – изучение особенностей проведения интратекального введения препаратов (начала терапии, суточной дозы и концентрации препарата, режима введения, сроков перезаправок), динамики спастичности, нарушений жизнедеятельности и качества жизни, эффективности и безопасности ITBтерапии у пациентов с ПСМТ.
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