Abstract
Leiomyomas are benign tumors which are predominantly found in the genitourinary and gastrointestinal tracts. Leiomyomas in the spine are extremely rare. The current study presents a case of a 35-year-old female with intraspinal leiomyoma who presented with low back pain and weakness in the left leg of two months. Computerized tomography and magnetic resonance imaging revealed an epidural mass at the T11–12 levels. The patient underwent a T11–12 laminectomy through posterior approach, achieving total removal of the tumor with a well-demarcated dissection plane. Pathological examination demonstrated a leiomyoma. Postoperatively, the patient showed a significant improvement in neurological function. Although intraspinal leiomyoma is extremely rare, it should be considered in the differential diagnosis of spinal lesions in females. The diagnosis is predominantly dependent on a pathological examination. Gross total resection is recommended for its treatment, however the prognosis remains poor. Post-operative hormonal therapy may be useful in controlling tumor recurrence.
Highlights
Leiomyomas are benign tumors composed of smooth muscle and vascular collagenous tissue mainly occurring in the uterus [1]
The present study reviews a case of intraspinal leiomyoma causing thoracic cord compression in a 19‐year‐old female
computed tomography (CT) of the spine disclosed an epidural mass with patchy calcification at the T11‐12 level, causing compression and deviation of the spinal cord
Summary
Leiomyomas are benign tumors composed of smooth muscle and vascular collagenous tissue mainly occurring in the uterus [1]. Leiomyomas usually cause spinal cord compression and must be surgically removed [1, 5]. The present study reviews a case of intraspinal leiomyoma causing thoracic cord compression in a 19‐year‐old female. A 19‐year‐old female presented to the Beijing Tiantan Hospital (Capital Medical University, Beijing, China) with numbness of the right lower extremities and severe progressive weakness in the right leg that had been apparent for two months. CT of the spine disclosed an epidural mass with patchy calcification at the T11‐12 level, causing compression and deviation of the spinal cord. A histopathological examination revealed that the tumor was composed of intersecting fascicles of acidophilic spindle cells with blunt‐ended nuclei, without significant cellular pleomorphism or mitotic activity (Fig. 3A). The patient was able to walk unaided and no recurrence or regrowth of the tumor was observed on follow‐up MRI after 25 months
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