Abstract
Male mice with septal lesions showed a dramatic postoperative increase in emotionality characterized by vigorous biting when restrained and exaggerated attempts to escape capture. In tests of intraspecific aggression they showed little or no fighting behavior and were defeated by normal or sham-lesioned controls. Pre-operative winning experience did not ameliorate the deficit in aggressive behavior. These results are contrary to those previously obtained with rats and hamsters and suggest a species-dependent effect of the lesion on aggressive behavior.
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