Abstract
Cholesterol granuloma is a rare lesion resulting from a granulomatous reaction containing cholesterol crystals. Such injury is often associated with sinus diseases, surgeries, and local trauma that can cause focal bleeding. This case refers to 2 lesions in the left maxilla and mandible in a 38-year-old female patient. The lesions were not related to sinus alterations; moreover, one was located in the mandible. Sagittal and axial tomographic sections showed a periapical hypodense area between teeth 24 and 25 and between teeth 34 and 35. Surgery was performed for total enucleation of both lesions. Histopathologic examination showed peripheral dense fibrous connective tissue and cracks compatible with regions of accumulation of cholesterol crystals in needle shapes, surrounded by macrophages and giant foreign-body cells. The case has 15 months of observation, with no recurrence and complete bone repair in the regions.
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