Abstract
Intraosseous (IO) blood samples can be used for routine laboratory studies. However, whether intraosseous samples are useful during CPR and drug infusions is unknown. We compared Na+, K+ and glucose levels from an IO cannula with central venous (CV) samples during CPR and after drug infusions. Piglets were mechanically ventilated and IO, carotid and PA cannulas inserted. Following hypoxic arrest, chest compressions and mechanical ventilation was resumed. During CPR, at 5, 10 and 15 min, animals received normal saline (NS, n=6), epinephrine (Epi, n=6), and sodium bicarbonate (NaHCO3, n=8) via IO. Blood from IO and CV were obtained pre-arrest (xx),and 5 min and 30 min of CPR. The table shows mean and r values at specified times. (p <.05 statistically significant)
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