Abstract
BackgroundLipomas are benign mesenchymal tumors composed of mature adipocytes. They are classified according to their histological pattern and their etiology remains unclear. Objectives: To present two cases and review the literature.Material and MethodsA search was conducted in the Medline / PubMed and Scielo data bases of the last 10 years (2004-2014) with the keywords “ intraoral lipoma OR oral cavity lipoma”.Results46 articles with 95 cases (56 women and 39 men) were reviewed. The average age was found to be 52.28 years (52.28 ± 18.55); and most of them occurred between the 4th and 6th decade of life. Lipomas occur mostly in the buccal mucosa (n = 36, 37.9%), followed by the tongue (n = 23, 24.2%) and other locations (n = 36, 37.9%). The most common histologic pattern was simple lipomas (n = 40, 42%), followed by fibrolipomas (n = 18, 18.9%) and other types (n = 37, 39.1%). The average tumor size was 19.77 ± 16.26mm.ConclusionsLipomas are a relatively rare finding in the oral cavity. Surgical excision is the treatment of choice and recurrence is not expected. Key words:Benign oral tumor, oral lipoma, lipoma, oral cavity.
Highlights
Lipoma is a benign mesenchymal tumor composed of mature adipocytes (1,2)
They are well circumscribed, painless and slow growing tumors (6-8). Their etiology and pathogenesis are not clear, even though factors like mechanical, endocrine, inflammatory (6,8-10), hypercholesterolemia and obesity (11,12), radiation (11) as well as chromosomal abnormalities (3,9,13) have been considered. They can be classified as simple lipoma, fibrolipoma, spindle cell lipoma, intramuscular lipoma, chondrolipoma, pleomorphic lipoma, myxoid lipoma, angiolipoma and sialolipoma (3,6,14)
157 articles were initially found, which after the application of the selection criteria were reduced to 40 case series and clinical case reports which included a total of 95 intraoral lipomas (Fig. 1)
Summary
Lipoma is a benign mesenchymal tumor composed of mature adipocytes (1,2) They are common in the head and neck region, but their appearance in the oral cavity is uncommon. The most common areas are the buccal mucosa, lips, tongue, palate,vestibule, floor of the mouth and retromolar area (5) They are well circumscribed, painless and slow growing tumors (6-8). Their etiology and pathogenesis are not clear, even though factors like mechanical, endocrine, inflammatory (6,8-10), hypercholesterolemia and obesity (11,12), radiation (11) as well as chromosomal abnormalities (3,9,13) have been considered. Lipomas are benign mesenchymal tumors composed of mature adipocytes. They are classified according to their histological pattern and their etiology remains unclear. Surgical excision is the treatment of choice and recurrence is not expected
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