Abstract
The intraoral cariogenicity of glucose, isomaltose, maltosylfructoside (4G-α-glucosylsucrose) and Coupling Sugar® were tested in the human mouth using two types (A and B) of intraoral cariogenicity test (ICT) systems. A-ICT system is a model for caries occurring at tooth sites which are protected from the influence of rapid cleaning by salivary flow and physical contact with tongue and cheeks. B-ICT system is a model for caries occurring at such exposed unprotected sites. The ICT results were characteristically different between the systems and showed an extremely wide variation among 20 subjects, but the intrasubject variations were relatively small.In comparison with sucrose supplementation, supplementation with the above sugars in the B-ICT strongly diminished not only the amounts and carbohydrate contents of ICT plaques but also the cell populations of Streptococcus mutans and lactobacilli in the plaques, but this did not occur in the A-ICT system. The intraoral cariogenicity of isomaltose and maltosylfructoside, which was evaluated by the extent of demineralization of the ICT slabs, was significantly less than that of sucrose in both the ICTs, while the reduced cariogenicity of glucose and Coupling Sugar® were only observed in the B-ICT.
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