Abstract
Introduction: Intraoperative analysis (IOA) of sentinel lymph nodes is effective, and reliable for assessing node in breast cancer allowing for immediate clearance. Metasin® is a quantitative PCR Assay that detects CK 19 and mammaglobin. ABS guidance does not advocate IOA methods after neo-adjuvant chemotherapy (NACT) due to concern regarding detection of residual disease. We completed a retrospective comparative review of all consecutive patients who had IOA during SNB following NACT.
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