Abstract
Multispectral and hyperspectral imaging (HSI) are emerging optical imaging techniques with the potential to transform the way surgery is performed but it is not clear whether current systems are capable of delivering real-time tissue characterization and surgical guidance. We conducted a systematic review of surgical in vivo label-free multispectral and HSI systems that have been assessed intraoperatively in adult patients, published over a 10-year period to May 2018. We analysed 14 studies including 8 different HSI systems. Current in-vivo HSI systems generate an intraoperative tissue oxygenation map or enable tumour detection. Intraoperative tissue oxygenation measurements may help to predict those patients at risk of postoperative complications and in-vivo intraoperative tissue characterization may be performed with high specificity and sensitivity. All systems utilized a line-scanning or wavelength-scanning method but the spectral range and number of spectral bands employed varied significantly between studies and according to the system's clinical aim. The time to acquire a hyperspectral cube dataset ranged between 5 and 30 seconds. No safety concerns were reported in any studies. A small number of studies have demonstrated the capabilities of intraoperative in-vivo label-free HSI but further work is needed to fully integrate it into the current surgical workflow.
Highlights
Multispectral and hyperspectral imaging (HSI) are emerging optical imaging techniques with the potential to radically transform the way surgery is performed
Several medical research multispectral and HSI systems have focused on the technique's diagnostic capabilities
We present a brief summary of the physical basis of HSI followed by a systematic review evaluating the intraoperative surgical applications of in vivo label-free, non-fluorescence multispectral and HSI
Summary
Multispectral and hyperspectral imaging (HSI) are emerging optical imaging techniques with the potential to radically transform the way surgery is performed. These optical imaging modalities are ideally suited for clinical use because they are non-contact, non-ionizing and non-invasive. Multispectral and HSI exploit the ability to split light into multiple narrow bands beyond the three conventional red, green and blue (RGB) visible spectral bands, enabling analysis of images not seen with the naked eye. With the development of high-resolution and fast frame rate multispectral and HSI cameras, enabling the capture of a rich imaging dataset at a video rate, these imaging methods offer great potential for real-time non-invasive tissue characterization and surgical guidance [21]
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
