Intraoperative MRI in glioma surgery: proof of benefit?

Abstract

Accurate and objective assessment of the extent of tumour removal during brain tumour surgery would aid surgeons and improve outcomes for patients. Thus, intraoperative imaging has gained increasing interest in the past decade because it allows surgeons to visualise and therefore attempt to remove tumour residues from incomplete resections in the same operation. By contrast with subjective estimation of the extent of resection by the surgeon, intraoperative imaging allows an objective measurement and provides quality-control feedback during surgery. Intraoperative MRI guidance and extent of resection in glioma surgery: a randomised, controlled trialOur study provides evidence for the use of intraoperative MRI guidance in glioma surgery: such imaging helps surgeons provide the optimum extent of resection. Full-Text PDF Intraoperative MRI-guided resection of glioblastoma multiforme: a systematic reviewWe did a systematic review to address the added value of intraoperative MRI (iMRI)-guided resection of glioblastoma multiforme compared with conventional neuronavigation-guided resection, with respect to extent of tumour resection (EOTR), quality of life, and survival. 12 non-randomised cohort studies matched all selection criteria and were used for qualitative synthesis. Most of the studies included descriptive statistics of patient populations of mixed pathology, and iMRI systems of varying field strengths between 0·15 and 1·5 Tesla. Full-Text PDF